The of role of synaptic depression and spike adaptation in perceptual memory of ambiguous visual stimulus sequences R J van Wezel1, C Klink2, W Woldman3, M te Winkel1, S van Gils3, H Meijer3 |
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1Donders Institute, Radboud University Nijmegen, Netherlands |
| Visual percept choices for sequences of repeated ambiguous stimuli depend on the time interval between subsequent stimulus presentations. Short blank intervals cause the percept to alternate, while at longer intervals the percept stabilizes into a single perceptual interpretation (perceptual memory). Here we show a biologically plausible computational model that describes the neuronal underpinnings of these choice dynamics. The model consists of excitatory and inhibitory tuned neurons and it includes, cross-inhibitory interactions, spike adaptation (with a short time constant) and synaptic depression (with a long time constant). Simulations of the model are consistent with our previous human psychophysical and monkey neurophysiological experimental data. The model predicts that adaptation and synaptic depression deterministically determine the transition from alternating to repeated percepts in sequences of ambiguous stimuli. Our model shows that no explicit (higher-order) memory or facilitatory component is necessary to explain perceptual memory effects in visual cortex. |
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